Toru Bando

Faculty & Position:Thoracic Surgery  doctor
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Last Updated: Sep. 09, 2019 at 11:42

Research Activities

Research Areas

  • Clinical surgery / Thoracic surgery
  • Clinical surgery / General surgery

Research Interests

    , p38 , JNK , mitogen activated protein kinase , Ex-vivo evaluation , EVLP , DDS

Published Papers

  • [Preoperative Arterial Embolization with N-butyl-2 Cyanoacrylate for Chronic Cavitary Pulmonary Aspergillosis with Trauma Induced Type Ⅰ Diabetes Mellitus].
    Nakanishi Yusuke;Kojima Fumitsugu;Kamo Minobu;Wakejima Ryo;Okura Mariko;Jinta Torahiko;Chonabayashi Naohiko;Bando Toru
    [Preoperative Arterial Embolization with N-butyl-2 Cyanoacrylate for Chronic Cavitary Pulmonary Aspergillosis with Trauma Induced Type Ⅰ Diabetes Mellitus]. 69(3) 2016
    :A 50-year-old man with hemoptysis, given a diagnosis of left upper lobe pulmonary aspergilloma with cavity and fungus ball by computed tomography. He has a history of typeⅠ diabetes mellitus due to traumatic injury of pancreas and underwent diaphragm plasty. Despite of systemic anti-fungal medication, symptom and radiological findings were not progressed and surgical intervention was planned. Bef
  • Experimental study in pulmonary artery sealing with a vessel-sealing device.
    Yamada Tetsu;Sowa Terumasa;Bando Toru;Date Hiroshi
    Experimental study in pulmonary artery sealing with a vessel-sealing device. 24(6) 2016
    BACKGROUND:The development of vessel-sealing devices will facilitate safety in video-assisted thoracoscopic surgery. Our objective was to evaluate the feasibility and safety of sealing pulmonary arteries with the Enseal tissue-sealing device.;METHODS:Pulmonary arteries from beagle dogs (mean body weight 13.1 kg, range 10.5-15.4 kg) were divided into 3 groups according to the in-vivo sealing method

Misc

  • IS-8-1 Virtual assisted lung mapping (VAL-MAP) for thoracoscopic sublobar lung resection : A novel operation-navigating strategy utilizing multiple bronchoscopic lung markings(IS-8 International Session (8) Thoracic surgery)
    佐藤 雅昭, 大政 貢, 山田 徹, 毛受 暁史, 陳 豊史, 佐藤 寿彦, 青山 晃博, 園部 誠, 板東 徹, 伊達 洋至
    Journal of Japan Surgical Society 115(2) Mar. 2014
  • Techniques for safe and efficient living-related donor operation in lobar lung transplantation
    Sato Masaaki, Yamada Tetsu, Aoyama Akihiro, Chen Fengshi, Sonobe Makoto, Bando Toru, Date Hiroshi
    The Journal of the Japanese Association for Chest Surgery 28(4) 439-445 2014
    We present techniques for safe and efficient donor operation in living related donor lobar lung transplantation. (1) Preparation for left atrium (LA) clamp slippage: after clamping the LA, we place stitches at each edge of the LA on the graft side of the clamp. In the event of clamp slippage after transecting the LA, the left atrial cut edge can be pulled by the stitches and re-clamped. (2) Bronchoscopic confirmation of bronchial transection site: to prevent separation of the superior segment bronchus and basal segment bronchus on right-side donor operation, a 25-gauge needle is inserted into the planned point of transection in the operative field and the locations of the needle and bronchial orifice are examined bronchoscopically. (3) Pulmonary artery plasty using a pericardial patch. (4) Easy pericardial closure: complications associated with pleural effusion are often encountered after the donor operation for living lung transplantation. Because direct closure of the open pericardium is difficult, a running stitch is placed between the anterior edge of the pericardium and posterior mediastinal pleura covering the esophagus (right) or descending aorta (left). In a retrospective analysis, the closure group (n=6) showed significantly smaller amounts of postoperative pleural effusion compared with the open group (n=13). Further studies evaluating the application of these techniques are necessary to demonstrate their contribution to improved quality and reduced complications in donor operation for living-related donor lobar lung transplantation.
  • Tracheobronchoplasty after induction chemoradiotherapy for squamous cell carcinoma of the lung: A case report
    Yamanashi Keiji, Yamada Tetsu, Aoyama Akihiro, Bando Toru, Date Hiroshi
    The Journal of the Japanese Association for Chest Surgery 28(5) 590-595 2014
    A 59-year-old man with a complaint of hemosputum was diagnosed with squamous cell carcinoma of the lung in the right upper lobe invading the trachea. After induction chemoradiotherapy, chest CT and FDG-PET showed a partial response. He underwent a right upper lobectomy and tracheobronchoplasty through a median sternotomy and right anterolateral thoracotomy. Because atypical cells were found in the margin of the proximal right main bronchus, additional resection of the right tracheal wall was required. After the tracheobronchial aperture was reduced in size, the bronchus intermedius was anastomosed to the smaller orifice. A pedicled omentum was prepared for wrapping the tracheobronchial anastomosis. The final pathological diagnosis was therapeutic effect Grade 3, and the postoperative course was uneventful except for transient atrial fibrillation.
  • A case of lung cancer with a thin-walled cavity detected concurrently with angiosarcoma of the scalp
    IKEDA Masaki, CHEN Fengshi, MIYATA Ryo, TAKAHASHI Koji, BANDO Toru, DATE Hiroshi
    The Journal of the Japanese Association for Chest Surgery 26(7) 753-756 Nov. 2012
    We report a case of lung cancer with a thin-walled cavity detected concurrently with angiosarcoma of the scalp. A 51-year-old man, who suffered from angiosarcoma of the scalp, presented with a mass of 6×8 mm, mainly containing a thin-walled cavity in the left lower lobe at the same time. After complete resection of the angiosarcoma of the scalp, we followed up the pulmonary lesion by administering Teceleukin, genetically recombinant IL-2, since we considered the pulmonary mass to most probably be metastasis of the angiosarcoma. During the treatment for six years after the surgery, although there was no apparent recurrent episode of angiosarcoma, the lung lesion gradually increased in size. Then, for diagnosis and treatment, we performed resection, and the lesion was diagnosed as a pulmonary adenocarcinoma. A cavitary lesion in the lung has the possibility of involving a wide variety of lung diseases. When a pulmonary cavitary lesion is detected concurrently with a disease which can metastasize to the lung and form a cavitary lesion in the lung, careful follow-up should be mandatory. In addition, if the lesion shows a clinical course inconsistent with a metastatic tumor, surgical biopsy should be performed without hesitation.
  • A case of pulmonary thromboembolism occurring just after discharge following lobectomy for lung cancer
    ZHANG Jitian, CHEN Fengshi, FUJINAGA Takuji, BANDO Toru, NIKI Shunitiro, DATE Hiroshi
    The Journal of the Japanese Association for Chest Surgery 25(2) 187-193 Mar. 2011
    A 76-year-old male underwent left upper lobectomy for primary lung cancer. Perioperative routine prophylaxis for pulmonary embolism was conducted. His postoperative course was without complications, and he was discharged on postoperative day (POD) 16. On the same day, he presented with dyspnea but stayed at home. Since the symptom did not improve, he came to the outpatient clinic 4 days later. He was readmitted with dehydration and slightly high CRP levels in laboratory tests. After hydration and low-level oxygen administration, his symptom markedly improved. On POD 26, a definitive diagnosis of pulmonary thromboembolism (PE) and deep vein thrombosis was made based on contrast-enhanced chest CT and lower extremity venous ultrasound. Anticoagulant therapy followed by IVC filter placement was performed immediately. The thrombi in the pulmonary vessels disappeared 3 weeks later, but there was no improvement in lower extremity venous thrombosis. The patient was discharged with the IVC filter in place. In the present case, it took almost one week to reach the final diagnosis after admission. In the case of postoperative dyspnea with nonspecific clinical findings in a thoracic surgery patient, we should always be aware of and actively suspect the possibility of PE, and effective treatments should be initiated immediately after its diagnosis.
  • Current status and the future of preservation for lung transplantation
    Fujinaga Takuji, Zhao Xiangdong, Sakamoto Jin, Nakajima Daisuke, Chen Fenshi, Shoji Tsuyoshi, Sakai Hiroaki, Bando Toru, Date Hiroshi
    Organ Biology 18(1) 127-129 2011
    Primary graft failure remains the main cause of early death after lung transplantation. Preservation conditions of donor grafts during ischemic time influences graft function after lung transplantation. This article describes current status of lung preservation for transplantation and our experiences of lung transplantation using ET-Kyoto solution developed in Kyoto University. Additionally, we present some results of our experiments for a novel preservation procedure of the lung.
  • Use of ET-Kyoto solution for organ preservation in living donor kidney transplantation : Report of initial experience
    IGUCHI Ryo, KANEMATSU Akihiro, WATANABE Jun, KAMBA Tomomi, KOTANI Hirokazu, YOSHIDA Hiroshi, ITO Noriyuki, YAMAMOTO Shingo, OKUNO Hiroshi, NAKAMURA Eijiro, NISHIYAMA Hiroyuki, KAMOTO Toshiyuki, BANDO Toru, OGAWA Osamu
    移植 44(5) 455-460 Oct. 2009
  • Osteosarcoma in the Anterior Chest Wall That Developed 20 Years After Postoperative Radiotherapy for Breast Cancer
    Murata Mariko, Shoji Tsuyoshi, Nakayama Ei, Bando Toru
    Japanese Journal of Lung Cancer 48(7) 807-810 Dec. 2008
    Background. Sarcomas are a rare complication of radiotherapy for breast cancer and such patients have a poor prognosis. We report resection of an osteosarcoma in the chest wall that developed 20 years after postoperative radiotherapy for breast cancer. Case. A 57-year-old woman was referred to our department for examination and treatment of an anterior chest wall tumor in April 2007. In September 1986, she had undergone a radical mastectomy and postoperative irradiation and chemotherapy for right breast cancer. In December 2003, she underwent chemotherapy for recurrence of breast cancer which was pointed out on computed tomography involving the pleura and left superior clavicular lymph nodes. In March 2006, follow-up computed tomography of the chest demonstrated the destruction of the sternum, which was diagnosed as recurrence and she was followed with chemotherapy for breast cancer continuously thereafter. In April 2007, because of the developing sternal tumor, excisional biopsy was performed and histopathology indicated sarcoma. In May 2007, resection of the chest wall tumor with the sternum, bilateral clavicles, bilateral first and second ribs, and right partial lung (upper and middle lobe) were performed, and the chest wall defect was reconstructed with a rectus abdominis musculocutaneous free flap. Histopathologically, the tumor was osteosarcoma with margin free. Conclusion. Adjuvant radiotherapy to the breast plays a significant role in preventing local disease recurrence in women treated for breast cancer. However, radiotherapy can induce malignant sarcoma after a latency period of several years. The risk is extremely low for the individual patient, but this disease is aggressive and associated with a poor overall prognosis. Therefore, early detection is necessary for optimal treatment and incisional biopsy is necessary for accurate diagnosis.
  • A Case of Endobronchial Mucoepidermoid Carcinoma of the Left Main Bronchus with Complete Left Lung Atelectasis
    Kiso Marina, Kondo Nobuyuki, Miyahara Ryo, Bando Toru, Sonobe Makoto, Wada Hiromi
    Japanese Journal of Lung Cancer 47(3) 263-267 Jun. 2007
    Background. In a case of a endobronchial tumor originating from a main bronchus presenting complete lung atelectasis, it is sometimes difficult to decide the peripheral resection line even with detailed imaging including multidimensional CT scan and MRI. Case. A 20-year-old woman with persistent hemoptysis was referred to our hospital because an occlusive tumor in the left main bronchus was detected with computed tomography. Fiberoptic bronchoscopy revealed that the tumor was 3 cm distal to the carina. The tumor was diagnosed as mucoepidermoid carcinoma pathologically. It was difficult to confirm the peripheral margin of the tumor, even with detailed imaging, because of the complete left lung atelectasis with mucoid-impaction. In the operative field, we opened a small window on the left upper lobe bronchus to confirm the peripheral margin of the tumor using a thin thoracoscope which revealed the extension of the tumor into the left upper lobe bronchus without invasion into the lower lobe bronchus. We performed left upper sleeve lobectomy, and achieved complete resection. Conclusion. When it is difficult to confirm the peripheral margin of the tumor, even with detailed imaging because of atelectasis, the method putting a thin thoracoscope or thin bronchoscope through a small bronchial incision during the operation is helpful to confirm the peripheral margin of the tumor and to decide the peripheral resection line.
  • PS-048-4 Perfusion but not inhalation of rhTRX ameliorates warm ischemia reperfusion injury
    張 吉天, 中村 隆之, 藤永 卓司, 陳 豊史, 青山 晃博, 岡本 俊宏, 浜川 博司, 阪井 宏彰, 板東 徹, 星野 勇馬, 淀井 淳二, 和田 洋巳, 中村 肇
    The journal of the Japanese Association for Chest Surgery 21(3) Apr. 2007
  • Malignant Melanoma of the Lung of Unknown Origin
    Okamoto Tamaki, Shoji Tsuyoshi, Bando Toru, Takahashi Tsuyoshi, Wada Hiromi
    Japanese Journal of Lung Cancer 47(1) 53-57 Feb. 2007
    We report a case of malignant melanoma of the lung of unknown origin. Case. A 50-year-old man was admitted to our hospital because of an abnormal shadow on chest roentgenogram and bilateral multiple pulmonary nodules on chest CT. Right upper lobectomy was carried out and the histological diagnosis of the tumor was malignant melanoma. Two nodules of the left lung were resected 1 month after the first operation, and they were also diagnosed as malignant melanoma. Although systemic examination was thoroughly performed, the original lesion was not detected. The color of the right second finger nail had changed to black about 10 years previously, but spontaneously regressed. Therefore the primary lesion might have been the finger nail. Although the patient underwent chemotherapy with DAV-Feron for 5 months after the second operation, metastatic lesions appeared in the lung, liver and vertebrae, and are now recently treatment. Conclusion. Malignant melanoma rarely originates in the lung and spontaneous regression often occurrs. Therefore, we should carefully search for the origin of pulmonary lesions.
  • A case of primary tracheal resection and reconstruction with suprahyoid release for adenoid cystic carcinoma of the trachea
    MURAOKA Yuki, OMASA Mitsugu, OKAMOTO Toshihiro, SHOJI Tsuyoshi, SAKAI Hiroaki, MIYAHARA Ryo, HANAOKA Nobuharu, BANDO Toru, FUKUSE Tatsuo, WADA Hiromi
    日本呼吸器外科学会雑誌 = The journal of the Japanese Association for Chest Surgery 20(7) 42-46 Nov. 2006
  • A case of primary tracheal resection and reconstruction with suprahyoid release for adenoid cystic carcinoma of the trachea
    Muraoka Yuki, Omasa Mitsugu, Okamoto Toshihiro, Shoji Tsuyoshi, Sakai Hiroaki, Miyahara Ryo, Hanaoka Nobuharu, Bando Toru, Fukuse Tatsuo, Wada Hiromi
    The journal of the Japanese Association for Chest Surgery 20(7) 928-932 Nov. 2006
    We report a case of 7 ring (3.5cm)-circumferential resection and end-to-end anastomosis of the trachea with suprahyoid release for adenoid cystic carcinoma. A 54-year-old man who had complained of dyspnea for over 6 months was referred to our hospital. Chest X ray, CT scan and respiratory examination revealed a midtracheal tumor, which was diagnosed as adenoid cystic carcinoma of the trachea. We performed 7 ring (3.5cm)-circumferential resection and end-to-end anastomosis of the trachea with suprahyoid release. Post-operative bronchofiberscopic findings showed good healing of the anastomotic site, and the post-operative course was uneventful. Suprahyoid release is a technically simple and useful procedure for extended upper and mid tracheal resection.
  • 7.CURRENT STRATEGY FOR PRIMARY MEDIASTINAL GERM CELL TUMORS
    Aoyama Akihiro, Bando Toru, Okubo Kenichi, Wada Hiromi
    Journal of Japan Surgical Society 107(6) 284-287 Nov. 2006
  • A lung transplant recipient with posttransplant lymphoproliferative disorder successfully treated with rituximab
    Aoyama Akihiro, Fukuse Tatsuo, Chen Fengshi, Hamakawa Hiroshi, Fujinaga Takuji, Omasa Mitsugu, Sakai Hiroaki, Hanaoka Nobuharu, Bando Toru, Hasegawa Seiki, Wada Hiromi
    The journal of the Japanese Association for Chest Surgery 20(6) 870-874 Sep. 2006
    Posttransplant lymphoproliferative disorder (PTLD) is a life-threatening complication after lung transplantation. This report describes the first case of PTLD in Japanese lung transplant recipients, which was successfully treated with rituximab. A 38-year-old man with emphysema underwent double lung transplantation and developed polymorphic PTLD in the allografts 4 months later. Immunosuppression therapy was reduced and immunoglobulin and antiviral drugs were administered. This therapy was not effective and resulted in acute rejection managed with steroid pulse therapy. We subsequently treated the patient using rituximab, an anti-CD20 monoclonal antibody. Thereafter, the lesions in both lungs regressed slightly, but remained present. Positron emission tomography with fluoro-2-deoxy-D-glucose (FDG-PET) showed no uptake in the thoracic fields, so we did not give the patient further courses of rituximab. One year after the diagnosis of PTLD, the nodules had almost completely disappeared and the patient presented no evidence of recurrence now.
  • S2-2 Lung transplantation at Kyoto University(Lung Transplantation-Present and Future-)
    板東 徹, 福瀬 達郎, 花岡 伸治, 阪井 宏彰, 大政 貢, 浜川 博司, 庄司 剛, 藤永 卓司, 近藤 展行, 陳 豊史, 青山 晃博, 松本 いずみ, 中村 隆之, 平田 敏樹, 米田 正始, 長谷川 誠紀, 和田 洋巳
    The journal of the Japanese Association for Chest Surgery 20(3) May 2006
  • Clinical application of ET-Kyoto solution for lung transplantation
    板東 徹, 福瀬 達郎, 青山 晃博, 陳 豊史, 藤永 卓司, 近藤 展行, 庄司 剛, 浜川 博司, 大政 貢, 阪井 宏彰, 中村 隆之, 花岡 伸治, 長谷川 誠紀, 米田 正始, 和田 洋巳
    Journal of Japan Surgical Society 107(2) Mar. 2006
  • Clinical application of an extracellular phosphate-buffered solution (Ep4) for lung preservation
    岡田 克典, 松村 輔二, 田畑 俊治, 佐渡 哲, 星川 康, 鈴木 聡, 伊達 洋至, 板東 徹, 近藤 丘
    The journal of the Japanese Association for Chest Surgery 19(3) May 2005
  • Lung retrieval from marginal donors and the non-heart-beating donors
    福瀬 達郎, 板東 徹, 中村 隆之, 青山 晃博, 陳 豊史, 藤永 卓司, 濱川 博司, 大政 貢, 阪井 宏彰, 花岡 伸治, 長谷川 誠紀, 和田 洋巳
    The journal of the Japanese Association for Chest Surgery 19(3) May 2005
  • 2. Development and Clinical Application of New ET-Kyoto Solution, an Extracellular Fluid Type Organ Preservation Solution Containing Trehalose and Vascular Endothelial Protective Agents
    FUJINAGA Takuji, NAKAMURA Takayuki, OMASA Mitsugu, HANAOKA Nobuharu, BANDO Toru, HASEGAWA Seiki, WADA Hiromi
    Cryobiology and cryotechnology 49(2) 107-108 Dec. 2003
    Although organ transplantation is established as a therapeutic procedure for various terminal organ dysfunctions, there are many unsolved problems such as shortage of donors and primary graft failure. A more reliable organ preservation solution could resolve these problems. Therefore, we have developed new ET-Kyoto solution characterized by extracellular type ion composition, non-reducing disaccharide of trehalose, and vascular endothelial protective agents (dibutyryl cAMP, nitroglycerin, N-acetyl cysteine). We confirmed the superior efficiency of the solution in canine lung transplantation and have applied it to clinical lung transplantation at Kyoto University Hospital since April 2002.
  • Clinical study of 20 resection cases of bronchopulmonary carcinoid
    Kamibayashi Takatoyo, Yanagihara Kazuhiro, Miyahara Ryow, Bandou Touru, Hasegawa Seiki, Inui Kenji, Wada Hiromi
    The journal of the Japanese Association for Chest Surgery 17(5) 566-569 Jul. 2003
    A total of 20 patients underwent thoracotomy and those diagnosed with bronchopulmonary carcinoid were clinically examined. The 5-year survival was 86.6% for typical cases and 60% for atypical cases. All stage I typical cases survived without recurrence, regardless of the type of operation. All atypical cases underwent lobectomy with dissection of mediastinal nodes. All three stage I atypical cases survived without recurrence. One stage IIIA patient and One stage IIIB patient showed distant metastasis and first died 10 months and the second 61 months postoperatively. Our findings indicate a good potential for limited operations for patients with typical cartinoid despite of T2 size. They also make clear the need for effective multimodarity therapy for patients with stage III atypical cartinoids.
  • A case of postoperative bronchial fistula successfully treated by omentopexy assisted by thoracoscopy
    Matsuoka Katsunori, Bando Toru, Wada Hiromi
    The journal of the Japanese Association for Chest Surgery 17(5) 574-577 Jul. 2003
    A 62-year-old woman suffered from prolonged bronchial fistula after resection of her right middle and lower lobes. She had received induction chemo-radiotherapy before the operation because of advanced-stage lung cancer. A bronchial fistula developed 14 months after the operation, and she underwent a muscle plombage operation, but eighteen months after the second operation, the bronchial fistula recurred. Closure of the bronchial fistula was attempted under bronchoscopy several times, but the fistula could not be closed. Therefore omentopexy assisted by thoracoscopy was performed, and after the third operation she is free of fistula symptoms and well with no evidence of recurrence. Thoracoscopy was useful even in treatment of bronchial fistula.
  • Two cases of successful treatment of locally advanced non-small cell lung cancer with induction chenio-radiotherapy using weekly carboplatin and paclitaxel
    Omasa Mitsugu, Yanagihara Kazuhiro, Otake Yosuke, Miyahara Ryo, Bando Toru, Tanaka Fumihiro, Hasegawa Seiki, Inui Kenji, Kitaichi Masanori, Wada Hiromi
    The journal of the Japanese Association for Chest Surgery 16(4) 574-579 May 2002
    We reported two cases of locally advanced non-small cell lung cancer successfully treated with induction chemo-radiotherapy using weekly carboplatin and paclitaxel. In case 1, a 71-year-old man had squamous cell carcinoma in the right upper lobe, and an undiagnosised tumor in the left S^6 field. After weekly chemotherapy with carboplatin at AUC 1.25 and paclitaxel 70mg/m^2 for 6 weeks that achieved a partial response, radiation therapy was administered to the right tumor. Right upper lobectomy was performed followed by left S^6 segmentectomy without operative complication. In case 2, a 65-year-old woman with an adenocarcinoma in the left S^6 was performed left pneumonectomy after induction concurrent chemo-radiotherapy with weekly carboplatin at AUC 1.25 plus paclitaxel 40mg/m^2 and radiation therapy that achieved a partial response without complication. Induction chemo-radiotherapy with weekly combined carboplatin and paclitaxel may be effective for locally invasive non-small cell lung cancer.
  • An operated case of bronchial mucoepidermoid carcinoma in a young man with mucoid impaction
    Ishikawa Shinya, Fukuse Tatsuo, Takahashi Ayuko, Ri Mio, Isowa Hirotaka, Bandou Touru, Tanaka Fumihiro, Hasegawa Seiki, Inui Kenji, Wada Hiromi, Ito Harumi
    The journal of the Japanese Association for Chest Surgery 16(1) 40-44 Jan. 2002
    A 25-year-old man was admitted to our hospital with abnormal shadow on chest X-ray detected at the onset of spontaneous pneumothorax. Chest radiograph showed a mass shadow with linear shadow. Chest CT film showed a tumor obstructing the left B^<9+10> and a lesion suspected of being mucoid impaction in the distal broncus of the tumor. Bronchoscopy revealed an endobronchial tumor, which almost completely occuluded the orifice of left B^<9+10>. Left lower segmentectomy with bronchoplasty was performed. The tumor was a polyp35×35×40mm in size and obstructed left B^<9+10> with mucoid impaction. Histologically the tumor was a low grade malignant mucoepidermoid carcinoma, and neither extrabronchial extension nor any lymphnode metastases were detected. Two years has passed with no evidence of recurrence. This case is considered interesting because the patient was treated for spontaneous pneumothorax on the side ipsilateral to the tumor, and massive mucoid impaction was seen.
  • A case of Pulmonary dilofilariasis diagnosed after thoracoscopic partial resection of the lung
    Matsumoto Seiji, Yanagihara Kazuhiro, Itou Sinya, Nakamura Takayuki, Ri Mio, Ootake Yousuke, Isowa Noritaka, Bandou Touru, Tanaka Fumihiro, Hasegawa Seiki, Inui Kenji, Wada Hiromi
    The journal of the Japanese Association for Chest Surgery 15(7) 806-809 Nov. 2001
    The patient was an 80-year-old woman who underwent surgery for right breast cancer at the age of 67 in 1987. In August 2000, chest X-ray showed a mass shadow in the right inferior lung field. In addition, chest CT revealed a non-calcified tumor with a flat margin measuring 1 cm in diameter located just below the right S^<10> pleura. In November 2000, thoracoscopic partial resection of the lung was performed to diagnose and treat the tumor. Although malignant cells were not detected by intraoperative histological examination, a diagnosis of pulmonary dilofilariasis was established after the histological examination of tissue specimens. Since the preoperative diagnosis of pulmonary dilofilariasis is difficult to establish, it is frequently detected by open lung biopsy. Therefore, since it is important to differentiate this lesion from other nodular lesions in the peripheral lung field, less invasive thoracoscopic lung biopsy is useful for establishing the definitive diagnosis of pulmonary dilofilariasis.
  • A case of Mycobacterium xenopi diagnosed with DNA-DNA hybridization for surgical specimens
    Sato Masaaki, Ike Osamu, Imanishi Naoko, Shoji Tsuyoshi, Nakayama Ei, Isowa Noritaka, Li Mio, Bando Toru, Tanaka Fumihiro, Hirata Toshiki, Fukuse Tatsuo, Hasegawa Seiki, Terada Yasuji, Wada Hiromi
    The journal of the Japanese Association for Chest Surgery 14(6) 703-707 Sep. 2000
    In Japan, pulmonary infection due to Mycobacterium xenopi(M.xenopi) is a quite rare nontuberculous mycobacteriosis. We experienced a case of pulmonary infection due to M.xenopi, which required surgical intervention for diagnosis, because lung cancer could not be ruled out on radiological studies. A 51-year-old asymptomatic man with abnormal shadow on chest x-ray was admitted. He had a history of heavy smoking and pulmonary emphysema. Chest CT scan demonstrated a mass with multiple small cavities at the apex of his right lung. Cytological and bacteriological sputum examination and bronchoscopic studies did not lead to diagnosis. Fluorodeoxyglucose positron emission tomography(FDG-PET) scan showed marked FDG uptake at the apex of his right lung, and lung cancer could not be ruled out. Partial resection of the lung including the mass was done. Microscopic studies of the specimen revealed caseous granuloma, which resembled tuberculoma. Postoperatively, the infectious agent was proved to be M.xenopi by DNA-DNA hybridization. He was treated with isoniazid, rifampicin, streptomycin, and ethambutol for three months. Six months postoperatively, no recurrence has been demonstrated.
  • TRACHEOBRONCHIAL STENTUS FOR MANAGEMENT OF AIRWAY STENOSTS
    Bando Toru, Mizuno Hiroshi, Terada Yasuji, Wada Hiromi, Hitomi Shigeki
    Journal of Japan Surgical Society 100(11) 735-738 Nov. 1999
  • Ultrastructural damage in lungs with 30-hour cold strage
    Kosaka Shinji, Ueda Mitsuhiro, Bando Toru, Liu Chun-Jan, Hitomi Shigeki, Wada Hiromi
    The journal of the Japanese Association for Chest Surgery 13(5) 614-626 Jul. 1999
    The present study was undertaken to clarify the effectiveness of new ET-Kyoto(nET)solution developed for long-term lung preservation by investigating ultrastructural damage in lungs preserved for 30 hours. Pairs of size-matched adult mongrel dogs were assigned randomly to three groups. In group A(n=7)lungs were flushed with nET, in group B(n=6)with University of Wisconsin(UW)solution, and in group C(n=6)with Low-Potassium-Dextran-Glucose(LPDG)solution. Lungs were flushed with each solution after vascular dilation with PGE_1 and stored at 4℃ for 30 hours. Ultrastructural damage of endothelial cells in small pulmonary artery(PA), namely protrusion of endothelial cells into vascular cavity, vacuolization, cellular destruction, detachment of endothelial cells from the basal lamina, rupture of the basal lamina, villi formation of the cell surface, and subendothelial structure destruction, were examined. For examination of alveolus, ultrastructural damage of the capillary endothelial cells(vacuolization, cellular destruction, detachment of the endothelial cells and villi formation), that of type I pneumocytes(vacuolization, cellular destruction, detachment and villi formation), and destruction of alveolar interstitum, were examined. Presence of blood cells and the debris of destroyed cells in the capillary space were also examined. Left single lung transplantation was performed, and arterial blood gas analysis was recorded every one hour until 6 hours after reperfusion. After sacrifice, transplanted lungs were excised and dried for evaluation of the wet to dry ratio(W/D). The frequency of cellular vacuolization in small PA evaluated as severe or moderate in group A(5.71±3.1%)tended to be lower than that in group B(24.4±7.4%)(p=0.053). The frequency of villi formation in small PA endothelial cells evaluated as severe in group A and B(2.85±2.0% , 3.33±2.3% respectively)was significant lower than that in group C(12.2±2.1%)(p=0.0072, 0.016 respectively). The frequency of subendothelial structure destruction in small PA evaluated as moderate or severe in group B(52.2±6.1%)was significantly lower that in group A(80.0±6.0%)(p=0.0088). The frequency of cellular destruction of capillary endothelial cells evaluated mild or severe in group C(22.2±2.8%)was significantly lower, and that in group A(34.2±6.9%)tended to be lower than that in group B(53.3±4.2%)(p=0.0088, 0.063 respectively). The frequency of villi formation of capillary endothelial cells evaluated severe in group B(2.22±1.4%)was significantly lower than that in group C(14.4±3.2%)and tended to be lower than that in group A(10.5±3.5%)(p=0.0098, 0.086 respectively). The frequency of cellular vacuolization of type I pneumocytes evaluated as mild or severe in group A and C(20.0±2.9%, 27.8±4.0% respectively)was significantly lower that in group B(47.8±6.8%)(p=0.0069, 0.034 respectively). The frequency of existence of debris in the capillary space in group A(25.7±3.1%)was significantly lower than that in group C(47.7±6.5%)(p=0.019). All animals in group A survived until the final assessment. In group B, four animals died by 6 hours after reperfusion and one animal in group C. Survival rate in group A was significantly higher than that in group B, and that in group C tended to be higher than that in group B. Pao_2 values in group A were significantly higher than those in group B until 3 hour-reperfusion and significantly higher than those in group B until 6 hour-reperfusion. The W/D of the transplanted lung in group A was significantly lower than those in groups B and C. These physiological results after reperfusion were compatible with the results of the examination of ultrastructural damege. We concluded that nET solution had better ability to maintain the ultrastructure of preserved lung compared with UW solution and LPDG solution. We supposed that this ability promoted excellent oxygenation ability of the transplanted lung after reperfusion.
  • A case report of thoracoscopic sympathectomy on buerger's disease : assessment based on laser doppler velocimetry
    Takahashi Tsuyoshi, Fukuse Tatsuo, Kurahashi Yasunori, Koba Takayuki, Takahashi Ayuko, Fukuda Seijun, Mega Seiji, Bando Toru, Tanaka Fumihiro, Hirata Toshiki, Oku Yoshitaka, Hasegawa Seiki, Terada Yasuji, Ike Osamu, Wada Hiromi, Hitomi Shigeki
    The journal of the Japanese Association for Chest Surgery 13(5) 685-689 Jul. 1999
    We report a successful case of bilateral thoracoscopic sympathectomy on a 46-year-old man suffering from severe coldness and numbness on his upper extremities caused by Buerger's disease. Under general anaesthesia, three ports were inserted through the third to fifth intercostal space, and sympathectomy was completed by resection of the second to fourth thoracic sympathetic ganglia. Immediately after the operation, his complaints markedly diminished;six weeeks after the operation, he obtained complete relief of the numbness and coldness, and the finger ulceration of fingers healed. Increase of the peripheral circulation of each finger assessed with a laser Doppler velocimeter(LDV)was well associated with the relief from his complaints. We concluded that LDV is a useful tool for the assessment of surgical treatment in patients with Buerger's disease.
  • A case of dumbbell tumor diagnosed with thin slice CT
    Aoyama Akihiro, Terada Yasuji, Hanaoka Nobuharu, Ueda Mitsuhiro, Bando Toru, Tanaka Fumihiro, Hirata Toshiki, Fukuse Tatsuo, Ike Osamu, Wada Hiromi, Hitomi Shigeki
    The journal of the Japanese Association for Chest Surgery 13(2) 191-194 Mar. 1999
    A 56-year-old man showed a mediastinal tumor on a screening chest computed tomography(CT)(10 mm gap and 7 mm slice)when he received radiotherapy for a pseudo-tumor in his left orbita. The mediastinal tumor was located beside the 9th to 11th thoracic vertebrae, but it was not clear if the lesion extended into the intervertebral foramen. Thin slice CT(5 mm gap and 3 mm slice), as preoperative imaging evaluation, revealed extension of the tumor into the intervertebral foramen, which lead to the diagnosis of dumbbell tumor. The tumor was resected by thoracotomy and hemilaminectomy and diagnosed as a ganglioneuroma. No postoperative or neurological complication was detected. The tumor near the intervertebral foramen should be scanned with thin slice CT before magnetic resonance imaging(MRI) or CT following myelography. If widening and expansion of the intervertebral foramen is revealed, MRI or CT following myelography should be additionally performed.
  • A Case of Foreign Body (The Obturator of a Lidocaine Spray Nozzle in the Respiratory Tract, Caused by Pretreatment for Upper Gastrointestinal Endoscopy
    Shoji Tsuyoshi, Hirata Toshiki, Fukuse Tatsuo, Ueda Mitsuhiro, Bando Toru, Tanaka Fumihiro, Terada Yasuji, Ike Osamu, Wada Hiromi, Hitomi Shigeki
    The journal of the Japan Society for Bronchology 20(4) 344-347 May 1998
    A 79-year-old woman was admitted to our hospital for further examination of a tracheal tumor shadow on chest computed tomograpy. Fiberoptic bronchoscopy revealed a tracheal tumor and a metallic foreign body in the trachea and right main bronchus. We removed the foreign body successfully by conventional forceps under fiberoptic bronchoscopy. The foreign body was an obturator of lidocaine spray nozzle, and was considered to have been caused by pharyngeal analgesia using a lidocaine spray before upper gastrointestinal endoscopy.
  • A case report of acute exacerbation of idiopathic pulmonary fibrosis after surgery for lung cancer
    Katakura Hiromichi, Yokomise Hiroyasu, Kanemitsu Naoki, Bando Toru, Kosaka Sinji, Okube Kenichi, Teramachi Masami, Takahashi Yutaka, Inui Kenji, Yagi Kazuyuki, Mizuno Hiroshi, Aoki Minoru, Wada Hiromi, Hitomi Shigeki
    The journal of the Japanese Association for Chest Surgery 8(2) 202-207 Mar. 1994
    A 63-year-old male was admitted because of an abnormal shadow on his chest x-ray. A transbronchial lung biopsy revealed squamous cell carcinoma and idiopathic pulmonary fibrosis. Mediastinoscopy, left upper lobectomy, partial resection of the left lower lobe and dissection of mediastinal lymph nodes were performed. On the 4th day after operation, PaO_2 was low and reticular shadows on chest x-ray were increased. Antibiotics and methylprednisolone (6g/day) were administered, but his condition did not improve, and he died on the 29th day after operation. Our experience indicates that when surgery is necessary for a patient with idiopathic pulmonary fibrosis, we must be very careful that the duration of the operation is short and the oxygen concentration must be less than 50% during the operation to prevent lung damage.
  • Greately improved respiratory function after two stage operation for bilateral giant emphysematous bullae : a case report
    Kanemitsu Naoki, Yokomise Hiroyasu, Katakura Hiromichi, Bandou Toru, Ohkubo Kenichi, Kosaka Shinji, Teramachi Masami, Takahashi Yutaka, Yagi Kazuyuki, Inui Kenji, Mizuno Hiroshi, Aoki Minoru, Wada Hiromi, Hitomi Shigeki
    The journal of the Japanese Association for Chest Surgery 8(2) 179-184 Mar. 1994
    A 34-year-old man admitted with dyspnea on effort as his chief complaint. A chest X-ray film showed bilateral giant bullae. A pulmonary angiogram showed adequate patency of the peripheral pulmonary vessels, so significant improvement of respiratory function was expected. He underwent two-stage bullectomy and plication successfully. Preoperative respiratory function test results were: VC 3.91l, %VC 93.8%, FEV_<1.0> 1.43l, FEV_<1.0>% 47.2%, PaO_2 64.7torr, PaCO_2 40.6torr, pH 7.427. Four months after surgery the results were : VC 5.01l %VC 120.1%, FEV_<1.0> 3.70l, FEV_<1.0>% 72.8%, PaO_2 81.7torr, PaCO_2 43.0torr, pH 7.403. Another remarkable finding was that his preoperative Holter ECG showed sick sinus syndrome, but immediately after the two stage operation it had disappeared.
  • Surgical treatment for small cell lung cancer; possible advantage of preoperative chemotherapy.
    Yokomise Hiroyasu, Bandou Touru, Ookubo Kenichi, Kosaka Shinji, Teramachi Masami, Takahashi Yutaka, Inui Kenji, Mizuno Hiroshi, Yagi Kazuyuki, Aoki Minoru, Wada Hiromi, Hitomi Shigeki
    The Journal of the Japanese Association for Chest Surgery 7(5) 541-546 1993
    In 46 patients who underwent surgery at our facility between 1976 and 1991 the histological diagnosis was small cell carcinoma of the lung. The results of treatment were assessed retrospectively. The clinical stage was I in 19 Patients, II in 7, III in 15 and IV in 5. Preoperative chemotherapy was given to 17 patients and postoperative chemotherapy in 23. The 5-year survival rate was 29%, and the median survival time (MST) was 87 weeks in those who had lung resection. The 5-year survival rates was 39%, 40% and 29% for pathological stages I, II and III, respectively. The 5-year survival rate was 30% in the preoperative chemotherapy group and 32% in the postoperative chemothrapy group. In the preoperative chemotherapy group, the 5-year survival rate was as high as 80% for clinical stage I and II, but it was only 38% in the postoperative chemotheray group. The clinical stage and the pathological stage showed a high inconsitency rate of 45.7%, reflecting the presence of advanced stages in many patients. It was considered that preoperative chemotherapy is useful in the surgical treatment of small cell carcinoma of the lung, regardless of its stage.
  • Sudden death caused by postoperative pulmonary thromboembolism : a case report
    Bando Toru, Hitomi Shigeki, Shindo Toru, Misaki Kohei, Chihara Koji
    呼吸器外科 : 日本呼吸器外科学会雑誌 4(4) 466-471 Aug. 1990
    A 51-year-old man had undergone colectomy for carcinoma of the colon was admitted with chief complaints of cough and chest pain. Chest x-ray films showed a mass lesion in the upper of the right lung field. SVC involvement was suggested by CT & MRI scans and SVC angiography. A right pneumonectomy was performed with combined resections of chest wall and pericardium. Six hours after the operation, circulatory collapse developed abruptly and the patient died despite cardiopulamonary resuscitation. An autopsy revealed that the cause of the death had been massive pulmonary thromboembolism which obstructed the left pulmonary artery almost completely. In this case, a preoperative angiographic study or operative procedures that could have caused the hemostasis of venous flow in SVC appeared to be responsible for the formation of the thrombus. Before operations on patients at high risk for pulmonary thromboembolism, preventive treatment, including the administration of antithrombotics, is recommended.
  • Sudden death caused by postoperative pulmonary thromboembolism. A case report.
    Bando Toru, Hitomi Shigeki, Shindo Toru, Misaki Kohei, Chihara Koji
    The Journal of the Japanese Association for Chest Surgery 4(4) 466-471 1990
    A 51-year-old man had undergone colectomy for carcinoma of the colon was admitted with chief complaints of cough and chest pain. Chest x-ray films showed a mass lesion in the upper of the right lung field. SVC involvement was suggested by CT & MRI scans and SVC angiography. A right pneumonectomy was performed with combined resections of chest wall and pericardium.
    Six hours after the operation, circulatory collapse developed abruptly and the patient died despite cardiopulmonary resuscitation. An autopsy revealed that the cause of the death had been massive pulmonary thromboembolism which obstructed the left pulmonary artery almost completely.
    In this case, a preoperative angiographic study or operative procedures that could have caused the hemostasis of venous flow in SVC appeared to be responsible for the formation of the thrombus.
    Before operations on patients at high risk for pulmonary thromboembolism, preventive treatment, including the administration of antithrombotics, is recommended.


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